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What prescription drugs should not be taken with CBD oil?

on November 03, 2022

Does CBD interact or interfere with medication? 

The following is provided for information purposes only and should not be used as a substitute for consultation with a healthcare professional.

"What prescription drugs should not be taken with CBD oil?" is a question that is on the minds of many people who are interested in taking CBD oil to improve their health. CBD can cause interactions with certain other prescription drugs. Doctors and researchers advise individuals using CBD to be cautious about mixing with any prescription medication they are taking.

They are advised to consult a healthcare professional about possible interactions because CBD has an impact on the way liver enzymes metabolise drugs. This can have an effect on the way the body processes some prescription medications. This could mean that you need to adjust the dose that you are taking or that the medications you are taking will not be as effective as it should be.

Drug interactions and CBD oil

As a general rule, CBD oil should not affect prescription medications, but research is continually taking place on medical and physical interactions with CBD. However, there are some medications that CBD can interact with, so it is important to check with the doctor who prescribes the medication in relation to drug metabolising before you start taking CBD oil.

Look to see if your prescription drug contains a grapefruit warning on the label. This advises against eating this citrus fruit for the duration of time you are taking the medication. Grapefruit is known to disrupt the activity of a group of proteins known as CYPs (Cytochrome P450 Enzymes or CYP450 Enzymes).

These enzymes deliver a medication's benefits to the intended target. The grapefruit disrupts the activity of CYPs and slows the way essential proteins break down medication. It can also increase the side effects and duration the drug stays in your system. So, if you see a grapefruit warning, definitely seek healthcare advice before proceeding or continuing with CBD oil.

Other factors relating to medications and CBD oil

The quality, purity and type of CBD oil all affects how it will interact with your medication and body. Honey Heaven take pride in highest-quality hemp that is organically and ethically grown by experienced and licensed farmers on outdoor farms in Switzerland. It is grown under the perfect and natural conditions such as sunlight and rainwater and using the traditional, natural methods.

Our quality control program is strict and detailed and tests every batch of products. The Full Spectrum Organic CBD Virgin Hemp Supercritical C02 Extract Boosted with Pure CBD Distillate we use is grown mainly for the extraction of CBD from its aerial's parts (stalk, leaves and flowers).

The result of this careful and selective farming is Honey Heaven's premium high-quality Full Spectrum Organic CBD Virgin Hemp Supercritical C02 Extract Boosted with Pure CBD Distillate. Read more about our Organic CBD products here, including the possible side effects of CBD and how our bodies process CBD:

Also, the timing of when you use CBD along with prescription drugs can also factor how the two may interact. And, of course, every individual responds differently to medications, depending on age, genetics, weight and many other factors.

CBD oil, common prescription and over-the-counter medications

There has been no research that conclusively warns patients against taking these drugs with CBD, and every patient's case is unique, meaning individuals should speak to their healthcare providers. As examples, you may experience increased side effects if CBD is used with these drugs:

  • Antidepressants: Due to possibility increasing the side effects of these medications, those who are interested in CBD should seek more information from their healthcare providers.
  • Anti-inflammatory Medicine: Potentially, CBD may increase the duration and strength of this over-the-counter medicine, thereby increasing the risk of adverse side effects. Patients should consult with their healthcare provider before taking this with CBD.
  • Blood Thinners: CBD can increase the effects of drugs used for blood-thinning by slowing down how the body metabolises them giving a prolonged presence in the system. Patients should consult with their healthcare provider before taking these with CBD.
  • Thyroid Medication: When taking common thyroid hormone replacement and anti-thyroid medications, patients who want to try CBD should consult with their healthcare provider.
  • Heart Medications: To avoid negative impact on blood pressure, you will need to consult your doctor as to whether to consume CBD.
  • Diabetes Medication: Although studies have found CBD has no significant impact on glucose levels, patients taking diabetes medication should talk to their doctor about whether CBD is right for them.
  • Benzodiazepines and Antipsychotics: Due to possibility increasing the side effects of these medications, those who are interested in CBD should seek more information from their healthcare providers.

Choose Honey Heaven's Organic CBD Products

We prioritise the highest standards of potency and purity possible to deliver only the best quality Full Spectrum Virgin Hemp CBD Extracts boosted with Pure CBD Distillate. Our CBD and phytonutrient content are confirmed and certified by independent laboratory tests.

At Honey Heaven, we are dedicated to producing and providing the healthiest and finest products by excluding all artificial preservatives, colours, flavourings, sweeteners and other foreign agents.

View Honey Heaven’s full range of CBD products, including CBD oil, which come with certificates of analysis based on laboratory test results, can be brought individually or as a gift set.


CBD Products are not meant to replace prescribed medication and are not intended for the treatment of serious medical conditions. Many medications are known to interact with other medications. Note that issues should not arise with topical CBD application, but always seek medical advice if unsure to avoid potential interaction. If you decide to take CBD with medication you should do so approximately 3 hours after.